Answer:
Ribosomes
Explanation:
Cellular fractionation consists of centrifugally separating the subcellular structures after cell disruption. Cells can be broken in many ways, the most common technique being a rotating plastic pestle inside a tube. The space between the pylon and the tube wall should be sufficient to break the cells causing minimal damage to the organites. After cell disruption, the resulting paste-like material is centrifuged to separate the organelles. The smallest organelle that can be isolated in this type of process is the ribosomes.