Answer:
Hypokalemia
Explanation:
The toxicity due to digoxin increases when metabolic disturbances such as hypokalemia occur. Â Hypokalemia usually occur during the diuretic therapy and leads to electrolytic disturbances. These disturbances increase the sensitivity of the digoxin to produce toxicity. In such scenarios, even a small concentration of digoxin serum can prove to be toxic. Hypokalemia inhibits the sodium-potassium ATPase and even treatment with antibodies specific to digoxin can lead to hypokalemia
