Answer:
The doctor will talk to the couple about having a child at this age. As there is a huge age gap in between these two partners.
The female is of age 28 and the male is of age 45. At such an age there are chances that the child borne can suffer from different genetic disorders but not by down syndrome.
This is so because the Down syndrome occurs when the age of female is more than 30 or 35 years of age.