Answer:
These options are true about DNA.
A. The 5' to 3' orientation of the new strand will depend upon where it is in the replication bubble relative to the position where replication first starts.
B. The new strand is the opposite of the template strand.
C. The new strand is an exact complement to the template strand.
Explanation:
Since the two strands of a DNA double helix are antiparallel, this 5′-to-3′ DNA synthesis can take place continuously on only one of the strands at a replication fork (the leading strand). On the lagging strand, short DNA fragments must be made by a “backstitching” process. The opposite strand with a base sequence directly corresponding to the mRNA sequence is refereed as coding strand. See images for clarification.
If you want to study more here is the reference:
Alberts B, Johnson A, Lewis J, et al. Molecular Biology of the Cell. 4th edition. New York: Garland Science; 2002. DNA Replication Mechanisms.
