Salmeterol is contraindicated based on his wife's condition.
Explanation:
The extra dose that the husband gave would lead to overdose of salmeterol causing serious side effects. Salmeterol is used to treat asthma. However, serious side effects may also happen due to acute overdose leading to worsening of asthma symptoms, breathing problems, sleep disturbances, muscle cramps, irregular rapid heartbeats, chest pain, fainting, seizure etc.
Hence Salmeterol should be given only per physician’s advice. In case of sudden flare-up of asthma or breathing problems, a rescue inhaler can be used instead of overdosing on Salmeterol.