Har Gobind Khorana and his colleagues performed numerous experiments translating synthetic mRNAs. In one experiment, an mRNA molecule with a repeating UG dinucleotide sequence was assembled and translated.
Write the sequence of this mRNA. Select all that apply.

a) 3'-GUGUGUGUGUGUGUGU...-5'
b) 5'-GUGUGUGUGUGUGUGU...-3'
c) 3'-UGUGUGUGUGUGUGUG...-5'
d) 5'-UGUGUGUGUGUGUGUG...-3'

Question

03-04-2020
Biology

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Har Gobind Khorana and his colleagues performed numerous experiments translating synthetic mRNAs. In one experiment, an mRNA molecule with a repeating UG dinucleotide sequence was assembled and translated.
Write the sequence of this mRNA. Select all that apply.

a) 3'-GUGUGUGUGUGUGUGU...-5'
b) 5'-GUGUGUGUGUGUGUGU...-3'
c) 3'-UGUGUGUGUGUGUGUG...-5'
d) 5'-UGUGUGUGUGUGUGUG...-3'

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KerryM KerryM · Answer 1 · 2020-04-09T11:16:53+02:00

KerryM KerryM

09-04-2020

Answer:

d) 5'-UGUGUGUGUGUGUGUG...-3'

Explanation:

A UG dinucleotide is when UG is repeated.

mRNAs are transcribed and translated as a 5' to 3' molecule. Therefore, the direction should be 5' - 3'.

For the mRNA to be in frame, it must start with UG. The only option that runs 5' - 3' and is in frame for a UG dinucleotide is d.

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luisvaschetto luisvaschetto · Answer 2 · 2021-10-28T18:27:38+02:00

The mRNA molecule with a repeating UG dinucleotide sequence is 5'-UGUGUGUGUGUGUGUG...-3' (Option D).

The ribonucleic acid (RNA) is a single strand molecule composed of a long chain of nucleotides added in a direction 5' to 3'.

The RNA polymerase always synthesizes an RNA strand in the 5' to 3' direction.

In RNA, there are four types of nucleotides, each one containing one different nitrogenous base, i.e., Uracil, Adenine, Cytosine and Guanine.

In this case, the nucleotide sequence is read as repeated dinucleotides of Uracil (U) and Guanine (G) in the 5' to 3' direction.

In conclusion, the mRNA molecule with a repeating UG dinucleotide sequence is 5'-UGUGUGUGUGUGUGUG...-3' (Option D).

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