If a candidate has no support in an entire region out of the one created, it is still indeed possible for them to win the Presidency.
If a lines are drawn across the U.S. such that they are divided into 4 regions:
An example that comes to mind is Abraham Lincoln. He had virtually no support in half the U.S. in 1860 and yet won the election on the votes of the Northern and Western states alone.
In conclusion, it is indeed possible to win if one has no support in one region.
Find out more about Lincoln's win at https://brainly.com/question/19462759.