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The karyotype of a child born with Down syndrome includes a trisomy in chromosome number 21. The rest of the karyotype remains normal.

What is a karyotype?

A karyotype is a representation to indicate the chromosomes of a somatic cell in an individual.

In humans, somatic cells are diploids, thereby karyotypes will be formed by two sets of homo-logous chromosomes.

Down syndrome is caused by the presence of an additional chromosome number 21, and therefore the karyotype will exhibit three (trisomy) 21 chromosomes.

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