Cytotoxic T cells kill their targets by programming them to undergo apoptosis. When cytotoxic T cells are mixed with target cells and rapidly brought into contact by centrifugation, they can program antigen-specific target cells to die within 5 minutes, although death may take hours to become fully evident.
In cellular immunity, a killer T cell identifies and kills a virus-infected cell because of the viral antigen on its surface, thus aborting the infection because a virus will not grow within a dead cell.
Thus, Cytotoxic T cells kill their targets by programming them to undergo apoptosis.
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