The release of myoglobin into the blood, caused by an electrical burn, can result in failure of the kidneys.
How does myoglobin result in kidney failure?
- Myoglobin protein is present in the striated muscles including skeletal and heart muscles. Unbound myoglobin when released into the blood can lead to renal (kidney) failure.
- Myoglobin is a heme- containing protein that binds to oxygen and supplies oxygen to the muscle cells (myocytes) for energy.
- When in blood, myoglobin can damage kidneys by resulting in intrarenal vasoconstriction, injury or obstruction to renal tube.
- Levels of myoglobin can increase due to heart attack, muscle injury and damage. This in turn leads to kidney failure.
- Myoglobin can result in increase in potassium levels in blood which disturbs the rhythm of heart.
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