The junctional folds and sarcolemma serve as the starting point for the excitation-contraction coupling events, which then move on through the T tubules and sarcoplasmic reticulum before acting at the sarcomere.
What takes place when a muscle contracts?
- Muscle contraction occurs when tension-producing areas within muscle cells are activated.
- Muscle tension can be generated without a change in muscle length, such as while keeping a heavy object in place, hence muscle contraction does not always imply muscle shortening in physiology.
- Actin and myosin filaments glide past one another to cause muscle contraction. It is generally accepted that cross-bridges that protrude from myosin filaments and engage in cyclic interactions with actin filaments when ATP is hydrolyzed are what propel this process.
- Action Potentials carried out via transverse tubules are performed by Ca2+ release channels in SR.
- Ca2+ spreads into the sarcoplasm.
- Troponin binds to Ca2+ to start contraction.
- AP activates voltage gated the T-tubules' Ca2+ channels
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