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Amphitrite1040
Hey there! 

The "driest" area of Midwest region would most likely:

[tex]Great \\ Plains [/tex]

Good luck on your assignment and enjoy your day! 

~[tex]MeIsKaitlyn:)[/tex]
catieetches

Answer:

The Great Plains are the driest.

Explanation:

All the others (Central Lowland, Interior Lowland, Superior Uplands) have some sort of water source to keep them somewhat wet.