Gene expression in eukaryotes can be regulated at various levels. Certain mutations in flies may cause them to develop an extra set of legs or wings.

A. Small Interfering RNA B. Operons C. Hox Genes, which determine the formation and arrangement of body parts in multicellular organisms, control gene expression by regulation of A. Pre mRNA Splicing B. mRNA Degradation C. DNA description.
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Hox genes are also called Homeotic genes.  In which they act as dictators on specific areas of an organism's body on when or where it should be developed. When these genes are overactivated or inactivated it may cause genetic disorders.

The right answers are: C. Hox Genes and C. DNA description (it's better to say transcription).

Hox genes are among the most extensively studied genes in evolutionary biology. Hox genes are a special category of homeotic genes. The homeotic genes have a DNA sequence described as homeotic or homeobox. Moreover their name, "Hox", comes from the contraction of "homeobox".

The homeobox will encode a homeodomain in translated proteins. These proteins are transcription factors (type of genetic regulatory protein) that, thanks to their homeodomain with a particular conformation, allows them to bind strongly to the DNA and allows cascade activation of other genes.