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Sickle cell disease results from an amino acid change from Valentine to glutamic acid. The result of this amino acid change is a deformed hemoglobin protein that does not carry oxygen well. What type of genetic mutation caused the amino acid change in a person with sickle cell anemia?

a. frameshift mutation
b. silent mutation
c. nonsense mutation
d. missense mutation

Respuesta :

D. Missense mutation.

A- the whole protein would be off, not just one AA
B- the disease wouldn’t occur
C - nonsense would end up in a truncated protein ((so shorter protein)

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